Endocrine Abstracts

Introduction: Weakness is one of the most common complaints among the patients. Clinical manifestations of a hypopituitarism depend on the extent of hormone deficiency and may be non-specific and thus the diagnosis is often missed. The progressive loss of pituitary hormone secretion is usually a slow process, which can occur over a period of months or years.Clinical case: A 62 years old women who complained of mild weakness mostly in the evenings in the ...

: Two-way interactions between thyroid and kidney functions are known. Chronic kidney disease (CKD) is accompanied by changes in synthesis, secretion, metabolism, and elimination of thyroid hormones, increased risk of hypothyroidism, rarely subclinical hyperthyroidism, whereas thyroid dysfunction affects physiology of the kidney, renal blood flow, glomerular filtration rate (GFR), tubular function, metabolism of water and electrolytes, and kidney structure. The aim of the stud...

Introduction: Thyrotoxic periodic paralysis (TPP) is very rare (prevalence in non-Asian populations 0.1–0.2%, more frequent in men) and potentially life-threatening complication of hyperthyroidism. TPP develops when thyroid hormones cause sodium-potassium-adenosine triphosphatase (Na/K-ATPase) pump overactivity, leading to rapid potassium shift into the cells resulting in hypokalaemia. This causes transient episode of muscular weakness usually involving lower limbs and hy...

Hyperprolactinaemia is a common endocrine disorder. Causes are related to physiological factors, pharmacological intervention and pathological conditions. There are a wide variety of drugs that can induce a significant hyperprolactinaemia frequently associated with clinical symptoms. The aim was to analyse clinical manifestation of hyperprolactinaemia in routine clinical practice.Material and methods: We conducted retrospective review of medical records ...